Trigohowilols A-G, Degraded Diterpenoids from the Stems of Trigonostemon howii

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	Trigohowilols A-G, Degraded Diterpenoids from the Stems of Trigonostemon howii
	Tang, Gui-Hua ; Zhang, Yu ; Yuan, Chun-Mao ; Li, Yan ; Gu, Yu-Cheng ; Di, Ying-Tong ; Wang, Yue-Hu ; Zuo, Guo-Ying ; Li, Shi-Fei ; Li, Shun-Lin ; He, Hong-Ping ; Hao, Xiao-Jiang
刊名	JOURNAL OF NATURAL PRODUCTS
	2012
卷号	75 期号:11 页码:1962-1966
关键词	DAPHNANE-TYPE DITERPENOIDS CHINENSIS HETEROPHYLLUS REIDIOIDES ALKALOIDS
ISSN号	0163-3864
中文摘要	Two new degraded diterpenoids, trigohowilols A (1) and B (2), four new heterodimers, trigohowilols C-F (3-6), one new homodimer, trigohowilol G (7), and three known degraded diterpenoids (8-10) were isolated from the methanol extract of the stems of Trigonostemon howii. Compounds 1-7 were evaluated for their cytotoxic activity against five human tumor cell lines by an MTT assay, and trigohowilols E (5) and F (6) exhibited inhibitory activity with IC50 values ranging from 2.33 to 12.57 mu M Moreover, compounds 1-6 showed weak antimicrobial activities (MIC values: 6.25-25 mu g/mL) against Staphylococcus aureus, Pseudomonas aeruginosa, MRSA 92(#), and MRSA 98(#) using a 2-fold dilution method.
收录类别	SCI
原文出处	10.1021/np3006315
语种	英语
公开日期	2016-05-12
内容类型	期刊论文
源URL	[http://ir.xtbg.org.cn/handle/353005/9828]
专题	西双版纳热带植物园_文献共享
推荐引用方式 GB/T 7714	Tang, Gui-Hua,Zhang, Yu,Yuan, Chun-Mao,et al. Trigohowilols A-G, Degraded Diterpenoids from the Stems of Trigonostemon howii[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(11):1962-1966.
APA	Tang, Gui-Hua.,Zhang, Yu.,Yuan, Chun-Mao.,Li, Yan.,Gu, Yu-Cheng.,...&Hao, Xiao-Jiang.(2012).Trigohowilols A-G, Degraded Diterpenoids from the Stems of Trigonostemon howii.JOURNAL OF NATURAL PRODUCTS,75(11),1962-1966.
MLA	Tang, Gui-Hua,et al."Trigohowilols A-G, Degraded Diterpenoids from the Stems of Trigonostemon howii".JOURNAL OF NATURAL PRODUCTS 75.11(2012):1962-1966.