Novel affinity monolithic column modified with cuprous sulfide nanoparticles for the selective enrichment of low-molecular-weight electron-rich analytes

	Novel affinity monolithic column modified with cuprous sulfide nanoparticles for the selective enrichment of low-molecular-weight electron-rich analytes
	Shan, Yuanhong; Shi, Xianzhe; Xu, Guowang
刊名	journal of separation science
	2015-03-01
卷号	38 期号:6 页码:982-989
关键词	Cuprous sulfide nanoparticles Electron-rich analytes Hybrid monolithic columns Kanamycin
英文摘要	a novel monolithic column modified with cuprous sulfide nanoparticles was developed and its affinity characteristics towards low-molecular-weight electron-rich analytes were investigated. in the synthesis process, home-made cuprous oxide nanocubes were immobilized on the surface of monolithic skeleton with the moderate thickness based on the strong interaction between imidazole groups and cuprous oxide, then the cuprous oxide layer was transformed into the more stable cuprous sulfide layer through the treatment by sodium sulfide. the resulting cuprous sulfide modified monolithic column presented good permeability and stability in a wide ph range from 2 to 10. two kinds of typical electron-rich analytes, kanamycin a and purine, were chosen to assess its affinity characteristics. compared with the commercial cu2+ -and ni2+-based affinity sorbents, a larger binding capacity of cuprous sulfide modified column toward kanamycin a was obtained under basic condition and the recovery of kanamycin a in a milk sample was over 70%. moreover, the binding capacity of cuprous sulfide modified column for purine was up to 5.57 mg/ml in frontal elution mode. these results suggested that the cu2s column has a promising application for the enrichment of electron-rich analytes.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, analytical
研究领域[WOS]	chemistry
关键词[WOS]	polyhedral oligomeric silsesquioxane ; performance liquid-chromatography ; porous polymer monoliths ; capillary electrochromatography ; kanamycin-a ; precolumn derivatization ; gold nanoparticles ; carbon nanotubes ; separation ; microextraction
收录类别	SCI
语种	英语
WOS记录号	WOS:000351598400013
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/146124]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Shan, Yuanhong,Shi, Xianzhe,Xu, Guowang. Novel affinity monolithic column modified with cuprous sulfide nanoparticles for the selective enrichment of low-molecular-weight electron-rich analytes[J]. journal of separation science,2015,38(6):982-989.
APA	Shan, Yuanhong,Shi, Xianzhe,&Xu, Guowang.(2015).Novel affinity monolithic column modified with cuprous sulfide nanoparticles for the selective enrichment of low-molecular-weight electron-rich analytes.journal of separation science,38(6),982-989.
MLA	Shan, Yuanhong,et al."Novel affinity monolithic column modified with cuprous sulfide nanoparticles for the selective enrichment of low-molecular-weight electron-rich analytes".journal of separation science 38.6(2015):982-989.