Facile Preparation of Core-Shell Magnetic Metal-Organic Framework Nanospheres for the Selective Enrichment of Endogenous Peptides
Xiong, Zhichao1,2; Ji, Yongsheng2,3; Fang, Chunli2; Zhang, Quanqing2; Zhang, Lingyi1; Ye, Mingliang2; Zhang, Weibing1,2; Zou, Hanfa2
刊名chemistry-a european journal
2014-06-10
卷号20期号:24页码:7389-7395
关键词core-shell structures magnetic properties metal-organic frameworks nanoparticles peptides
英文摘要facile preparation of core-shell magnetic metal-organic framework nanospheres by a layer-by-layer approach is presented. the nanospheres have high surface area (285.89 cm(2)g(-1)), large pore volume (0.18 cm(3)g(-1)), two kinds of mesopores (2.50 and 4.72 nm), excellent magnetic responsivity (55.65 emu g(-1)), structural stability, and good dispersibility. the combination of porosity, hydrophobicity, and uniform magnetism was exploited for effective enrichment of peptides with simultaneous exclusion of high molecular weight proteins. the nanospheres were successfully applied in the selective enrichment of endogenous peptides in human serum.
WOS标题词science & technology ; physical sciences
类目[WOS]chemistry, multidisciplinary
研究领域[WOS]chemistry
关键词[WOS]mesoporous silica microspheres ; tof ms analysis ; mass-spectrometry ; chromatographic-separation ; biomedical applications ; nanoparticles design ; sio2 shell ; serum ; hybrid ; extraction
收录类别SCI
语种英语
WOS记录号WOS:000337617500026
公开日期2016-05-09
内容类型期刊论文
源URL[http://cas-ir.dicp.ac.cn/handle/321008/145583]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Dept Chem & Mol Engn, Shanghai 200237, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
3.Henan Univ Tradit Chinese Med, Coll Pharm, Zhengzhou 450008, Peoples R China
推荐引用方式
GB/T 7714
Xiong, Zhichao,Ji, Yongsheng,Fang, Chunli,et al. Facile Preparation of Core-Shell Magnetic Metal-Organic Framework Nanospheres for the Selective Enrichment of Endogenous Peptides[J]. chemistry-a european journal,2014,20(24):7389-7395.
APA Xiong, Zhichao.,Ji, Yongsheng.,Fang, Chunli.,Zhang, Quanqing.,Zhang, Lingyi.,...&Zou, Hanfa.(2014).Facile Preparation of Core-Shell Magnetic Metal-Organic Framework Nanospheres for the Selective Enrichment of Endogenous Peptides.chemistry-a european journal,20(24),7389-7395.
MLA Xiong, Zhichao,et al."Facile Preparation of Core-Shell Magnetic Metal-Organic Framework Nanospheres for the Selective Enrichment of Endogenous Peptides".chemistry-a european journal 20.24(2014):7389-7395.
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