Electrochemical biosensing platform based on amino acid ionic liquid functionalized graphene for ultrasensitive biosensing applications

	Electrochemical biosensing platform based on amino acid ionic liquid functionalized graphene for ultrasensitive biosensing applications
	Lu, Xianbo; Wang, Xue; Jin, Jing; Zhang, Qing; Chen, Jiping
刊名	biosensors & bioelectronics
	2014-12-15
卷号	62 期号:1 页码:134-139
关键词	Biosensor Graphene Ionic liquids Electronic conductivity Tyrosinase
通讯作者	卢宪波 ; 陈吉平
英文摘要	in this study, a facile non-covalent method was developed for preparing water-soluble graphene with excellent electronic conductivity. room temperature ionic liquids (ils) with high ionic conductivity were used for the non-covalent surface functionalization of graphene through pi-pi stacking interactions. compared to other ils used, amino acid ionic liquids (aails) were found to be the most effective for improving the dispersion of graphene in water phase. electrochemical and spectroscopic results confirmed that the obtained aail functionalized gr can retain the excellent electronic conductivity of pristine graphene without damaging the graphene lattice. the obtained water-soluble graphene (gr-aail) was exemplified to fabricate an electrochemical biosensor using tyrosinase as a model enzyme, and the sensitivity (12,600 ma cm(-2) m-1) of gr-aail based biosensor was about 17 times higher than that of graphene oxide and other nanomaterial based biosensor, displaying its unprecedented high sensitivity for biosensing. the detection limit for catechol (one important environmental pollutant) reached as low as 8 nm with a response time of 3 s and a linear range from 25 nm to 11,100 nm. the aail-gr based biosensor also demonstrated good reproducibility, repeatability, selectivity, long-term stability and high recovery for catechol detection. amino acid ionic liquid functionalized graphene proves to be a robust and versatile electrochemical biosensing platform for fabricating biosensors with excellent performance. (c) 2014 elsevier b.v. all rights reserved.
学科主题	物理化学
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biophysics ; biotechnology & applied microbiology ; chemistry, analytical ; electrochemistry ; nanoscience & nanotechnology
研究领域[WOS]	biophysics ; biotechnology & applied microbiology ; chemistry ; electrochemistry ; science & technology - other topics
关键词[WOS]	glassy-carbon electrode ; water-soluble graphene ; tyrosinase biosensor ; gold nanoparticles ; mesoporous carbon ; rapid detection ; composite ; chitosan ; catechol ; electrocatalysis
收录类别	SCI
语种	英语
WOS记录号	WOS:000340334800022
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/144095]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Lu, Xianbo,Wang, Xue,Jin, Jing,et al. Electrochemical biosensing platform based on amino acid ionic liquid functionalized graphene for ultrasensitive biosensing applications[J]. biosensors & bioelectronics,2014,62(1):134-139.
APA	Lu, Xianbo,Wang, Xue,Jin, Jing,Zhang, Qing,&Chen, Jiping.(2014).Electrochemical biosensing platform based on amino acid ionic liquid functionalized graphene for ultrasensitive biosensing applications.biosensors & bioelectronics,62(1),134-139.
MLA	Lu, Xianbo,et al."Electrochemical biosensing platform based on amino acid ionic liquid functionalized graphene for ultrasensitive biosensing applications".biosensors & bioelectronics 62.1(2014):134-139.