Tunable Bronsted Acidity-Dependent Alkylation and Alkenylation of Indoles

	Tunable Bronsted Acidity-Dependent Alkylation and Alkenylation of Indoles
	Wu, Kaikai 1; Wu, Ping 1; Wang, Liandi 1; Chen, Jiping 1; Sun, Chenglin 1; Yu, Zhengkun 1,2
刊名	advanced synthesis & catalysis
	2014-12-15
卷号	356 期号:18 页码:3871-3880
关键词	alkenylation alkylation Bronsted acids 3-(dimethylamino)acrylonitrile indoles
通讯作者	余正坤
英文摘要	the bronsted acid-mediated alkylation and alkenylation of indoles were efficiently achieved by means of 3-(dimethylamino)acrylonitrile. regulating the acidity of the reaction medium with para-toluenesulfonic acid monohydrate (p-tsoh center dot h2o) and/or acetic acid (hoac) led to versatile formation of 3-alkylated and 3-alkenylated indole derivatives under mild conditions. the 3-alkylated indole products could be nearly quantitatively transformed to the corresponding separable (e)- and (z)-3-alkenylated indoles.
学科主题	物理化学
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, applied ; chemistry, organic
研究领域[WOS]	chemistry
关键词[WOS]	c-h activation ; bond activation ; practical synthesis ; functionalization ; alkenes ; c2-alkenylation ; 2-alkylation ; derivatives ; olefination ; aldehydes
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000346071600020
公开日期	2016-05-09
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/144082]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Liaoning, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
推荐引用方式 GB/T 7714	Wu, Kaikai,Wu, Ping,Wang, Liandi,et al. Tunable Bronsted Acidity-Dependent Alkylation and Alkenylation of Indoles[J]. advanced synthesis & catalysis,2014,356(18):3871-3880.
APA	Wu, Kaikai,Wu, Ping,Wang, Liandi,Chen, Jiping,Sun, Chenglin,&Yu, Zhengkun.(2014).Tunable Bronsted Acidity-Dependent Alkylation and Alkenylation of Indoles.advanced synthesis & catalysis,356(18),3871-3880.
MLA	Wu, Kaikai,et al."Tunable Bronsted Acidity-Dependent Alkylation and Alkenylation of Indoles".advanced synthesis & catalysis 356.18(2014):3871-3880.