The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes

CORC > 苏州纳米技术与纳米仿生研究所 > 中国科学院苏州纳米技术与纳米仿生研究所 > 纳米仿生研究部 > 靳健团队

	The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes
	Yang, J; Jiang, J（靳健）
刊名	NANOSCALE
	2013
卷号	5 期号:9 页码:3834-3840
关键词	ANTIBACTERIAL ACTIVITY NEGATIVE BACTERIA ESCHERICHIA-COLI IONS
通讯作者	Yang, YY
英文摘要	Silver nanoparticles are of great interest for use as antimicrobial agents. Studies aimed at producing potent nano-silver biocides have focused on manipulation of particle size, shape, composition and surface charge. Here, we report the cell penetrating peptide catalyzed formation of antimicrobial silver nanoparticles in N, N-dimethylformamide. The novel nano-composite demonstrated a distinctly enhanced biocidal effect toward bacteria (Gram-positive Bacillus subtilis, Gram-negative Escherichia coli) and pathogenic yeast (Candida albicans), as compared to triangular and extremely small silver nanoparticles. In addition, a satisfactory biocompatibility was verified by a haemolysis test. Our results provide a paradigm in developing strategies that can maximize the silver nanoparticle application potentials while minimizing the toxic effects.
收录类别	SCI ; EI
语种	英语
WOS记录号	WOS:000317859400036
公开日期	2014-01-15
内容类型	期刊论文
源URL	[http://ir.sinano.ac.cn/handle/332007/1370]
专题	苏州纳米技术与纳米仿生研究所_纳米仿生研究部_靳健团队
推荐引用方式 GB/T 7714	Yang, J,Jiang, J. The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes[J]. NANOSCALE,2013,5(9):3834-3840.
APA	Yang, J,&Jiang, J.(2013).The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes.NANOSCALE,5(9),3834-3840.
MLA	Yang, J,et al."The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes".NANOSCALE 5.9(2013):3834-3840.