Molecular-Level Insights into Intrinsic Peroxidase-Like Activity of Nanocarbon Oxides

	Molecular-Level Insights into Intrinsic Peroxidase-Like Activity of Nanocarbon Oxides
	Zhao RS(赵瑞生); Zhao, RS; Gao XF(高兴发); Zhao, X; Gao, XF
刊名	CHEMISTRY-A EUROPEAN JOURNAL
	2015
卷号	21 期号:3 页码:960-964
关键词	carboxyl density functional calculations nanocarbon oxides peroxidase reaction mechanism
通讯作者	高兴发
英文摘要	Nanocarbon oxides have been proved to possess great peroxidase-like activity, catalyzing the oxidation of many peroxidase substrates, such as 3,3,5,5-tetramethylbenzidine (TMB) and o-phenylenediamine dihydrochloride (OPD), accompanied by a significant color change. This chromogenic reaction is widely used to detect glucose and occult blood. The chromogenic reaction was intensively investigated with density functional theory and molecular-level insights into the nature of peroxidase-like activity were gained. A radical mechanism was unraveled and the carboxyl groups of nanocarbon oxides were identified as the reactive sites. Aromatic domains connected with the carboxyl groups were critical to the peroxidase-like activity.
学科主题	Chemistry
类目[WOS]	Chemistry, Multidisciplinary
收录类别	SCI ; EI
WOS记录号	WOS:000347615200002
公开日期	2016-05-03
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/228151]
专题	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Zhao RS,Zhao, RS,Gao XF,et al. Molecular-Level Insights into Intrinsic Peroxidase-Like Activity of Nanocarbon Oxides[J]. CHEMISTRY-A EUROPEAN JOURNAL,2015,21(3):960-964.
APA	赵瑞生,Zhao, RS,高兴发,Zhao, X,&Gao, XF.(2015).Molecular-Level Insights into Intrinsic Peroxidase-Like Activity of Nanocarbon Oxides.CHEMISTRY-A EUROPEAN JOURNAL,21(3),960-964.
MLA	赵瑞生,et al."Molecular-Level Insights into Intrinsic Peroxidase-Like Activity of Nanocarbon Oxides".CHEMISTRY-A EUROPEAN JOURNAL 21.3(2015):960-964.