High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging

	High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging
	Wu, Z; Gao, K; Chen, J; Wang, DJ; Wang, SH; Chen, H; Bao, Y; Shao, QG; Wang, ZL; Zhang, K
刊名	MEDICAL PHYSICS
	2015
卷号	42 期号:2 页码:741-749
关键词	grating-based phase contrast imaging information extraction methods signal-to-noise ratio sensitivity
英文摘要	Purpose: Grating-based x-ray phase contrast imaging is considered as one of the most promising techniques for future medical imaging. Many different methods have been developed to retrieve phase signal, among which the phase stepping (PS) method is widely used. However, further practical implementations are hindered, due to its complex scanning mode and high radiation dose. In contrast, the reverse projection (RP) method is a novel fast and low dose extraction approach. In this contribution, the authors present a quantitative analysis of the noise properties of the refraction signals retrieved by the two methods and compare their sensitivities. Methods: Using the error propagation formula, the authors analyze theoretically the signal-to-noise ratios (SNRs) of the refraction images retrieved by the two methods. Then, the sensitivities of the two extraction methods are compared under an identical exposure dose. Numerical experiments are performed to validate the theoretical results and provide some quantitative insight. Results: The SNRs of the two methods are both dependent on the system parameters, but in different ways. Comparison between their sensitivities reveals that for the refraction signal, the RP method possesses a higher sensitivity, especially in the case of high visibility and/or at the edge of the object. Conclusions: Compared with the PS method, the RP method has a superior sensitivity and provides refraction images with a higher SNR. Therefore, one can obtain highly sensitive refraction images in grating-based phase contrast imaging. This is very important for future preclinical and clinical implementations. (C) 2015 American Association of Physicists in Medicine.
学科主题	Radiology, Nuclear Medicine & Medical Imaging
类目[WOS]	Radiology, Nuclear Medicine & Medical Imaging
收录类别	SCI
WOS记录号	WOS:000349229600023
公开日期	2016-05-03
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/228125]
专题	高能物理研究所_多学科研究中心
推荐引用方式 GB/T 7714	Wu, Z,Gao, K,Chen, J,et al. High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging[J]. MEDICAL PHYSICS,2015,42(2):741-749.
APA	Wu, Z.,Gao, K.,Chen, J.,Wang, DJ.,Wang, SH.,...&吴自玉.(2015).High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging.MEDICAL PHYSICS,42(2),741-749.
MLA	Wu, Z,et al."High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging".MEDICAL PHYSICS 42.2(2015):741-749.