Visual search in Alzheimer's disease - fMRI study

	Visual search in Alzheimer's disease - fMRI study
	Hao, J; Li, KC; Li, K; Zhang, DX; Wang, W; Yan, B; Yang, YH; Wang, Y; Chen, Q; Shan, BC
刊名	MEDICAL IMAGING AND AUGMENTED REALITY, PROCEEDINGS
	2004
卷号	3150 页码:#REF!
通讯作者	Hao, J (reprint author), Capital Univ Med Sci, Xuanwu Hosp, Dept Radiol, Beijing 100053, Peoples R China.
英文摘要	The aim was to investigate the neural basis of visual attention deficits in Alzheimer's disease (AD) patients using functional MRI. Thirteen AD patients and 13 age-matched controls participated in the experiment of two visual search tasks, one was a pop-out task, the other was a conjunction task. The fMRI data were collected on a 1-5T MRI system and analyzed by SPM99. Both groups revealed almost the same networks engaged in both tasks, including the superior parietal lobule (SPL), frontal and occipito-temporal cortical regions (OTC), primary visual cortex and some subcortical structures. AD patients have a particular impairment in the conjunction task. The most pronounced differences were more activity in the SPL in controls and more activity in the OTC in AD patients. These results imply that the mechanisms controlling spatial shifts of attention axe impaired in AD patients.
学科主题	Computer Science; Radiology, Nuclear Medicine & Medical Imaging
类目[WOS]	Computer Science, Interdisciplinary Applications ; Computer Science, Theory & Methods ; Radiology, Nuclear Medicine & Medical Imaging
收录类别	SCI
WOS记录号	WOS:000223567700025
公开日期	2016-05-03
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/226923]
专题	高能物理研究所_多学科研究中心
推荐引用方式 GB/T 7714	Hao, J,Li, KC,Li, K,et al. Visual search in Alzheimer's disease - fMRI study[J]. MEDICAL IMAGING AND AUGMENTED REALITY, PROCEEDINGS,2004,3150:#REF!.
APA	Hao, J.,Li, KC.,Li, K.,Zhang, DX.,Wang, W.,...&单保慈.(2004).Visual search in Alzheimer's disease - fMRI study.MEDICAL IMAGING AND AUGMENTED REALITY, PROCEEDINGS,3150,#REF!.
MLA	Hao, J,et al."Visual search in Alzheimer's disease - fMRI study".MEDICAL IMAGING AND AUGMENTED REALITY, PROCEEDINGS 3150(2004):#REF!.