Cytotoxic Potential of Silver Nanoparticles

	Cytotoxic Potential of Silver Nanoparticles
	Zhang TL(张田露); Wang LM(王黎明); Zhang, TL; Wang, LM; Chen, Q; Chen, CY; Chen CY(陈春英)
刊名	YONSEI MEDICAL JOURNAL
	2014
卷号	55 期号:2 页码:283-291
关键词	Silver nanoparticles cell effects cytotoxicity genotoxicity immunological response risk assessment
英文摘要	Silver nanoparticles (AgNPs) have been widely used in industrial, household, and healthcare-related products due to their excellent antimicrobial activity With increased exposure of AgNPs to human beings, the risk of safety has attracted much attention from the public and scientists. In review of recent studies, we discuss the potential impact of AgNPs on individuals at the cell level. In detail, we highlight the main effects mediated by AgNPs on the cell, such as cell uptake and intracellular distribution, cytotoxicity, genotoxicity, and immunological responses, as well as some of the major factors that influence these effects in vitro and in vivo, such as dose, time, size, shape, surface chemistry, and cell type. At the end, we summarize the main influences on the cell and indicate the challenges in this field, which may be helpful for assessing the risk of AgNPs in future.
学科主题	General & Internal Medicine
收录类别	SCI
WOS记录号	WOS:000331916800001
公开日期	2016-05-03
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/225387]
专题	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Zhang TL,Wang LM,Zhang, TL,et al. Cytotoxic Potential of Silver Nanoparticles[J]. YONSEI MEDICAL JOURNAL,2014,55(2):283-291.
APA	张田露.,王黎明.,Zhang, TL.,Wang, LM.,Chen, Q.,...&陈春英.(2014).Cytotoxic Potential of Silver Nanoparticles.YONSEI MEDICAL JOURNAL,55(2),283-291.
MLA	张田露,et al."Cytotoxic Potential of Silver Nanoparticles".YONSEI MEDICAL JOURNAL 55.2(2014):283-291.