Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa | |
Zhang H(张衡); Gao ZQ(高增强); Zhang, H; Gao, ZQ; Su, XD; Dong, YH;; Dong YH(董宇辉) | |
刊名 | FEBS LETTERS |
2012 | |
卷号 | 586期号:19页码:3193-3199 |
英文摘要 | The type VI secretion systems (T6SS) have emerging roles in interspecies competition. In order to have an advantage in defense against other organisms, this system in Pseudomonas aeruginosa delivers a peptidoglycan amidase (Tse1) to the periplasmic space of a competitor. An immune protein (Tsi1) is also produced by the bacterium to protect itself from damage caused by Tse1. Tsi1 directly interacts with Tse1. We report that the crystal structure of Tse1 displays a common CHAP protein fold. Strikingly, our structures showed that the third residue in the catalytic triad may be novel as this residue type has not been observed previously. (C) 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved. |
学科主题 | Biochemistry & Molecular Biology; Biophysics; Cell Biology |
收录类别 | SCI |
WOS记录号 | WOS:000309314200031 |
公开日期 | 2016-05-03 |
内容类型 | 期刊论文 |
源URL | [http://ir.ihep.ac.cn/handle/311005/224227] |
专题 | 高能物理研究所_多学科研究中心 |
推荐引用方式 GB/T 7714 | Zhang H,Gao ZQ,Zhang, H,et al. Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa[J]. FEBS LETTERS,2012,586(19):3193-3199. |
APA | 张衡.,高增强.,Zhang, H.,Gao, ZQ.,Su, XD.,...&董宇辉.(2012).Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa.FEBS LETTERS,586(19),3193-3199. |
MLA | 张衡,et al."Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa".FEBS LETTERS 586.19(2012):3193-3199. |
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