Comparative investigations on the biological effects of As (III) and As (V) in clam Ruditapes philippinarum using multiple biomarkers

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Comparative investigations on the biological effects of As (III) and As (V) in clam Ruditapes philippinarum using multiple biomarkers
	Ji, CL; Xu, H; Wang, Q; Zhao, JM; Wu, HF
刊名	FISH & SHELLFISH IMMUNOLOGY
	2015-11-01
卷号	47 期号:1 页码:79-84
关键词	Ruditapes philippinarum Arsenic Biological effects Metabolomics
ISSN号	1050-4648
通讯作者	Wu, HF (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China. hfwu@yic.ac.cn
产权排序	[Ji, Chenglong; Wang, Qing; Zhao, Jianmin; Wu, Huifeng] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China; [Ji, Chenglong; Wang, Qing; Zhao, Jianmin; Wu, Huifeng] YICCAS, Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China; [Xu, Hai'e] Nanjing Med Univ, Affiliated Hosp 2, Clin Nutr, Nanjing 210011, Jiangsu, Peoples R China
英文摘要	Inorganic arsenic is a known pollutant with two chemical forms, arsenite (As (III)) and arsenate (As (V)), in marine environment. Clam Ruditapes philippinarum is an important fishery species along the Bohai coast. In this study, the biological effects induced by the two arsenic chemical forms (arsenite and arsenate) were compared using multiple biochemical indices in the digestive glands of clam R. philippinarum. The production of reactive oxygen species, antioxidant enzyme activities and metabolic responses exhibited that both As (III) and As (V) induced immune, oxidative and osmotic stresses in clam digestive glands. The differential metabolic biomarkers, histidine and taurine, indicated the differential responsive mechanisms in osmotic regulation in clam digestive glands. In addition, both arsenic treatments enhanced the anaerobiosis metabolism in clam digestive glands. Overall, this work illustrated that arsenite and arsenate induced similar biological effects in clams, which might be accounted for the biological transformation of arsenate to arsenite in clams. (C) 2015 Elsevier Ltd. All rights reserved.
研究领域[WOS]	Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences
关键词[WOS]	MUSSEL MYTILUS-GALLOPROVINCIALIS ; NMR-BASED METABOLOMICS ; VENERUPIS-PHILIPPINARUM ; BIVALVE MOLLUSKS ; ARSENIC EXPOSURE ; RESPONSES ; IDENTIFICATION ; CHALLENGE ; PROFILES ; ALANINE
收录类别	SCI
语种	英语
WOS记录号	WOS:000365053300009
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/9538]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室海岸带生物资源高效利用研究与发展中心
推荐引用方式 GB/T 7714	Ji, CL,Xu, H,Wang, Q,et al. Comparative investigations on the biological effects of As (III) and As (V) in clam Ruditapes philippinarum using multiple biomarkers[J]. FISH & SHELLFISH IMMUNOLOGY,2015,47(1):79-84.
APA	Ji, CL,Xu, H,Wang, Q,Zhao, JM,&Wu, HF.(2015).Comparative investigations on the biological effects of As (III) and As (V) in clam Ruditapes philippinarum using multiple biomarkers.FISH & SHELLFISH IMMUNOLOGY,47(1),79-84.
MLA	Ji, CL,et al."Comparative investigations on the biological effects of As (III) and As (V) in clam Ruditapes philippinarum using multiple biomarkers".FISH & SHELLFISH IMMUNOLOGY 47.1(2015):79-84.