Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via 'click chemistry'

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室 > 海岸带生物学与生物资源利用所重点实验室

	Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via 'click chemistry'
	Tan, WQ ; Li, Q; Li, WC ; Dong, F; Guo, ZY
刊名	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
	2016
卷号	82 页码:404-410
关键词	Starch derivatives Click chemistry Antioxidant activity
ISSN号	0141-8130
通讯作者	Guo, ZY (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China. zhanyongguo@hotmail.com
产权排序	[Tan, Wenqiang; Li, Qing; Li, Wancong; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Tan, Wenqiang; Li, Wancong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
英文摘要	Based on the copper (I) catalyzed Huisgen azide-alkyne cycloaddition (click chemistry), the novel synthesis of a variety of 1,2,3-triazole-linked starch derivatives was developed, including 6-hydroxymethyltriazole-6-deoxy starch (HMTST), 6-hydroxyethyltriazole-6-deoxy starch (HETST), 6-hydroxypropyltriazole-6-deoxy starch (HPTST), and 6-hydroxybutyltriazole-6-deoxy starch (HBTST). Their antioxidant properties against hydroxyl-radical, DPPH-radical, and superoxide-radical were evaluated in vitro, respectively. The antioxidant activity of the obtained novel amphiprotic starch derivatives via 'click reaction' exhibited remarkable improvement over starch. And the scavenging effect indices of most of the products were higher than 60% at 1.6 mg/mL against hydroxyl-radical and DPPH-radical. Moreover, the scavenging effect of the products against superoxide-radical attained 90% above at 0.1 mg/mL. Generally, the antioxidant activity decreased in the order: HBTST > HPTST > HETST >HMTST > starch. Furthermore, the order of their antioxidant activity was consistent with the electron-donating ability of different substituted groups of the 1,2,3-triazoles. The substituted groups with stronger electron supplying capacity provided more electrons to the various radicals, which relatively enhanced the capacity for scavenging free radicals. (c) 2015 Elsevier B.V. All rights reserved.
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
关键词[WOS]	BIOLOGICAL EVALUATION ; ANTIBACTERIAL ; CHITOSAN ; AMYLASE ; CYTOTOXICITY ; SILATRANES ; SILYLATION ; INULIN ; AGENTS ; CELLS
收录类别	SCI
语种	英语
WOS记录号	WOS:000367425100052
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/9307]
专题	烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室烟台海岸带研究所_污染过程与控制实验室海岸带生物资源高效利用研究与发展中心
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat 2.Univ Chinese Acad Sci
推荐引用方式 GB/T 7714	Tan, WQ,Li, Q,Li, WC,et al. Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via 'click chemistry'[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2016,82:404-410.
APA	Tan, WQ,Li, Q,Li, WC,Dong, F,&Guo, ZY.(2016).Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via 'click chemistry'.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,82,404-410.
MLA	Tan, WQ,et al."Synthesis and antioxidant property of novel 1,2,3-triazole-linked starch derivatives via 'click chemistry'".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 82(2016):404-410.