Synthesis of Functional Adsorption Resin and Its Adsorption Properties in Purification of Flavonoids from Hippophae rhamnoides L. Leaves

CORC > 兰州化学物理研究所 > 中国科学院兰州化学物理研究所 > 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室

	Synthesis of Functional Adsorption Resin and Its Adsorption Properties in Purification of Flavonoids from Hippophae rhamnoides L. Leaves
	Lou S(娄嵩)1,2,3; Chen ZB(陈振斌)1,2,4; Liu YF(刘永峰)1,2,3 ; Ye HL(叶鹤林)1,2,3; Di DL(邸多隆)1,2 ; Di DL(邸多隆)
刊名	Industrial and Engineering Chemistry Research
	2012
卷号	51 期号:6 页码:2682-2696
ISSN号	0888-5885
通讯作者	邸多隆
英文摘要	The efficient purification method of high purity flavonoids from Hippophae rhamnoides L. (sea buckthorn) was reported. A series of adsorption resins with novel structure were synthesized on the basis of the Friedel-Crafts catalyzed and amination reaction. Functional groups, such as the chloromethyl or the amino group, were introduced into the resin matrix, respectively, to raise the specific surface area, produce the hydrogen-bonding interaction, and enhance the adsorption selectivity toward flavone compounds. The results showed that the adsorbent DDM-1 with 0.44 mmol/g chloromethyl groups and the adsorbent DDM-2 with 0.68 mmol/g amino groups performed high purity and adsorption to flavone compounds in Hippophae rhamnoides L. leaves, respectively, obviously higher than that from commercial adsorbents due to their more pores, higher surface area and pore size, and stronger hydrogen-bonding interaction between flavonoids and surface functional groups of the adsorbents, which maintained the adsorption driving force. The isotherms and kinetics of synthetic resins were also studied systematically. In order to get the optimal sample, the No. 3 and No. H were selected and used in the developed two-separation-step protocol due to their high adsorption and purity capacities, respectively. The purity of flavonoids after the two steps was increased 6.62-fold from 5.55% to 36.75%. The method showed its universality via good effects on the purification of flavonoids from Hippophae rhamnoides L. leaves.
学科主题	分析化学与药物化学
收录类别	SCI
资助信息	the Hundred Talents Program of the Chinese Academy of science (CAS);the National Natural Science Foundation of China (NSFC, no. 20974116)
语种	英语
WOS记录号	WOS:000300211800023
公开日期	2016-02-26
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/19343]
专题	兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
通讯作者	Di DL(邸多隆)
作者单位	1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem NW Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 4.Lanzhou Univ Technol, State Key Lab Gansu Adv Nonferrous Met Mat, Lanzhou 730050, Peoples R China
推荐引用方式 GB/T 7714	Lou S,Chen ZB,Liu YF,et al. Synthesis of Functional Adsorption Resin and Its Adsorption Properties in Purification of Flavonoids from Hippophae rhamnoides L. Leaves[J]. Industrial and Engineering Chemistry Research,2012,51(6):2682-2696.
APA	Lou S,Chen ZB,Liu YF,Ye HL,Di DL,&邸多隆.(2012).Synthesis of Functional Adsorption Resin and Its Adsorption Properties in Purification of Flavonoids from Hippophae rhamnoides L. Leaves.Industrial and Engineering Chemistry Research,51(6),2682-2696.
MLA	Lou S,et al."Synthesis of Functional Adsorption Resin and Its Adsorption Properties in Purification of Flavonoids from Hippophae rhamnoides L. Leaves".Industrial and Engineering Chemistry Research 51.6(2012):2682-2696.