Determination of diethylstilbestrol in milk using carbon nanotube-reinforced hollow fiber solid-phase microextraction combined with high-performance liquid chromatography

CORC > 兰州化学物理研究所 > 中国科学院兰州化学物理研究所 > 中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室

	Determination of diethylstilbestrol in milk using carbon nanotube-reinforced hollow fiber solid-phase microextraction combined with high-performance liquid chromatography
	Yang Y(杨阳)1,2,3; Chen J(陈娟)1,2 ; Shi YP(师彦平)1,2
刊名	Talanta
	2012
卷号	97 页码:222-228
关键词	Multi-walled carbon nanotubes Hollow fiber solid-phase microextraction High-performance liquid chromatography Diethylstilbestrol Sol-gel technology
ISSN号	0039-9140
通讯作者	陈娟 ; 师彦平
英文摘要	Carbon nanotube-reinforced hollow fiber solid-phase microextraction (CNTs-HF-SPME) combined with high-performance liquid chromatography (HPLC) was used to extract and determine diethylstilbestrol (DES) in milk products. Wall pores of the hollow fiber were filled with multi-walled carbon nanotubes (MWCNTs) using sol–gel technology. In the proposed method, DES was selectively extracted by MWCNTs, desorbed to methanol, and analyzed by HPLC. The parameters affecting the efficiency of CNTs-HFSPME, such as the length of the hollow fiber, extraction and desorption times, extraction temperature, stirring rate, pH of the sample solution, and the amount of organic solvent and salt in the sample solution, were investigated and optimized. Under the optimized extraction conditions, the method showed good linearity (24–960 μg L⁻¹), a low method detection limit (MDL, 5.1 μg L⁻¹), and good recoveries at four different concentrations. It was proven to be simple, rapid, sensitive, and solvent free for the analysis of DES in dairy products.
学科主题	分析化学与药物化学
收录类别	SCI
资助信息	the National Nature Science Foundation of China (No. 21075127;21105106)
语种	英语
WOS记录号	WOS:000308268800032
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/19328]
专题	兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室
作者单位	1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem NW Plant Resources, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Yang Y,Chen J,Shi YP. Determination of diethylstilbestrol in milk using carbon nanotube-reinforced hollow fiber solid-phase microextraction combined with high-performance liquid chromatography[J]. Talanta,2012,97:222-228.
APA	Yang Y,Chen J,&Shi YP.(2012).Determination of diethylstilbestrol in milk using carbon nanotube-reinforced hollow fiber solid-phase microextraction combined with high-performance liquid chromatography.Talanta,97,222-228.
MLA	Yang Y,et al."Determination of diethylstilbestrol in milk using carbon nanotube-reinforced hollow fiber solid-phase microextraction combined with high-performance liquid chromatography".Talanta 97(2012):222-228.