Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells
Dong,Fa-Wu; Wu,Zhi-Kun; Yang,Liu; Zi,Chen-Ting; Yang,Dan; Ma,Rui-Jing; Liu,Zhen-Hua; Luo,Huai-Rong; Zhou,Jun; Hu,Jiang-Miao
刊名PHYTOCHEMISTRY
2015-10-01
卷号118页码:51-60
关键词Valeriana stenoptera Valerianaceae Iridoids Sesquiterpenoids Biological activity
英文摘要Twenty-one compounds (nine iridoids and twelve sesquiterpenoids), including ten previously unknown (five iridoids and five sesquiterpenoids) were isolated from whole dried material of Valeriana stenoptera. Structures were established on the basis of extensive spectroscopic analysis and the relative stereochemistry of 13-hydroxypatchoulol A was further confirmed by X-ray crystallographic data. All isolates were evaluated for their effects on nerve growth factor (NGF)-mediated neurite outgrowth in pheochromocytoma (PC12) cells and seven compounds showed potent promoting effects. (C) 2015 Elsevier Ltd. All rights reserved.
类目[WOS]Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]NERVE GROWTH-FACTOR ; OFFICINALIS VAR. LATIFOLIA ; NARDOSTACHYS-CHINENSIS ; BIOLOGICAL-ACTIVITY ; ACYLATED IRIDOIDS ; JATAMANSI JONES ; ALPHA-GUAIENE ; ROOTS ; CONSTITUENTS ; GLYCOSIDES
收录类别SCI
语种英语
WOS记录号WOS:000363076800007
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/25201]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式
GB/T 7714
Dong,Fa-Wu,Wu,Zhi-Kun,Yang,Liu,et al. Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells[J]. PHYTOCHEMISTRY,2015,118:51-60.
APA Dong,Fa-Wu.,Wu,Zhi-Kun.,Yang,Liu.,Zi,Chen-Ting.,Yang,Dan.,...&Hu,Jiang-Miao.(2015).Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells.PHYTOCHEMISTRY,118,51-60.
MLA Dong,Fa-Wu,et al."Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells".PHYTOCHEMISTRY 118(2015):51-60.
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