Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells | |
Dong,Fa-Wu; Wu,Zhi-Kun; Yang,Liu; Zi,Chen-Ting; Yang,Dan; Ma,Rui-Jing; Liu,Zhen-Hua; Luo,Huai-Rong; Zhou,Jun; Hu,Jiang-Miao | |
刊名 | PHYTOCHEMISTRY |
2015-10-01 | |
卷号 | 118页码:51-60 |
关键词 | Valeriana stenoptera Valerianaceae Iridoids Sesquiterpenoids Biological activity |
英文摘要 | Twenty-one compounds (nine iridoids and twelve sesquiterpenoids), including ten previously unknown (five iridoids and five sesquiterpenoids) were isolated from whole dried material of Valeriana stenoptera. Structures were established on the basis of extensive spectroscopic analysis and the relative stereochemistry of 13-hydroxypatchoulol A was further confirmed by X-ray crystallographic data. All isolates were evaluated for their effects on nerve growth factor (NGF)-mediated neurite outgrowth in pheochromocytoma (PC12) cells and seven compounds showed potent promoting effects. (C) 2015 Elsevier Ltd. All rights reserved. |
类目[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
研究领域[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
关键词[WOS] | NERVE GROWTH-FACTOR ; OFFICINALIS VAR. LATIFOLIA ; NARDOSTACHYS-CHINENSIS ; BIOLOGICAL-ACTIVITY ; ACYLATED IRIDOIDS ; JATAMANSI JONES ; ALPHA-GUAIENE ; ROOTS ; CONSTITUENTS ; GLYCOSIDES |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000363076800007 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn/handle/151853/25201] |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
推荐引用方式 GB/T 7714 | Dong,Fa-Wu,Wu,Zhi-Kun,Yang,Liu,et al. Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells[J]. PHYTOCHEMISTRY,2015,118:51-60. |
APA | Dong,Fa-Wu.,Wu,Zhi-Kun.,Yang,Liu.,Zi,Chen-Ting.,Yang,Dan.,...&Hu,Jiang-Miao.(2015).Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells.PHYTOCHEMISTRY,118,51-60. |
MLA | Dong,Fa-Wu,et al."Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells".PHYTOCHEMISTRY 118(2015):51-60. |
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