Pestalpolyols A-D, Cytotoxic Polyketides from Pestalotiopsis sp cr013

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Pestalpolyols A-D, Cytotoxic Polyketides from Pestalotiopsis sp cr013
	Li,Jing; Xie,Jin; Yang,Yin-He; Li,Xiao-Lian; Zeng,Ying; Zhao,Pei-Ji
刊名	PLANTA MEDICA
	2015-09-01
卷号	81 期号:14 页码:1285-1289
关键词	Pestalotiopsis sp cr013 Amphisphaeriaceae pestalpolyol X-ray crystallography polyketide cytotoxic activity
英文摘要	Four novel polyketides, named pestalpolyols A (1), B (2), C (3), and D (4), were isolated from solid fermentation products of Pestalotiopsis sp. cr013. Their structures were elucidated by extensive spectroscopic methods, including 1D and 2Dnuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry experiments, and the absolute configuration was confirmed by single-crystal X-ray diffraction analysis using the anomalous scattering of Cu K radiation. The inhibitory activities of compounds 1, 2, and 4 against five human tumor lines were tested in vitro, and showed IC50 values 2.3-31.2 mu M.
类目[WOS]	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]	Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]	MICROSPORA ; METABOLITE ; HAWAII ; ACID
收录类别	SCI
语种	英语
WOS记录号	WOS:000361681000008
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/25150]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Li,Jing,Xie,Jin,Yang,Yin-He,et al. Pestalpolyols A-D, Cytotoxic Polyketides from Pestalotiopsis sp cr013[J]. PLANTA MEDICA,2015,81(14):1285-1289.
APA	Li,Jing,Xie,Jin,Yang,Yin-He,Li,Xiao-Lian,Zeng,Ying,&Zhao,Pei-Ji.(2015).Pestalpolyols A-D, Cytotoxic Polyketides from Pestalotiopsis sp cr013.PLANTA MEDICA,81(14),1285-1289.
MLA	Li,Jing,et al."Pestalpolyols A-D, Cytotoxic Polyketides from Pestalotiopsis sp cr013".PLANTA MEDICA 81.14(2015):1285-1289.