Koumine, Humantenine, and Yohimbane Alkaloids from Gelsemium elegans

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Koumine, Humantenine, and Yohimbane Alkaloids from Gelsemium elegans
	Xu, You-Kai; Yang, Lin; Liao, Shang-Gao; Cao, Pei; Wu, Bin; Hu, Hua-Bin; Guo, Juan; Zhang, Ping
刊名	JOURNAL OF NATURAL PRODUCTS
	2015-07-01
卷号	78 期号:7 页码:1511-1517
英文摘要	Nine new alkaloids of the koumine (1-4), humantenine (5-7), and yohimbane (8, 9) types as well as 12 known analogues were isolated from the leaves and vine stems of Gelsemium elegans. Compound 1 is the first N-4-demethyl alkaloid of the koumine type, compound 7 is the first nor-humantenine alkaloid, and compounds 8 and 9 are the first N-1-oxide and the first seco-E-ring alkaloids, respectively, of the yohimbane type. Compounds 1 and 7 exhibited moderate cytotoxicity against five human tumor cell lines with IC50 values in the range 4.6-9.3 mu M.
类目[WOS]	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]	Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]	INDOLE ALKALOIDS ; OXINDOLE ALKALOIDS ; ROUTE
收录类别	SCI
语种	英语
WOS记录号	WOS:000358700000005
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/25082]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	Xu, You-Kai,Yang, Lin,Liao, Shang-Gao,et al. Koumine, Humantenine, and Yohimbane Alkaloids from Gelsemium elegans[J]. JOURNAL OF NATURAL PRODUCTS,2015,78(7):1511-1517.
APA	Xu, You-Kai.,Yang, Lin.,Liao, Shang-Gao.,Cao, Pei.,Wu, Bin.,...&Zhang, Ping.(2015).Koumine, Humantenine, and Yohimbane Alkaloids from Gelsemium elegans.JOURNAL OF NATURAL PRODUCTS,78(7),1511-1517.
MLA	Xu, You-Kai,et al."Koumine, Humantenine, and Yohimbane Alkaloids from Gelsemium elegans".JOURNAL OF NATURAL PRODUCTS 78.7(2015):1511-1517.