Performance investigation of SP3 and diffusion approximation for three-dimensional whole-body optical imaging of small animals

CORC > 自动化研究所 > 中国科学院自动化研究所 > 中国科学院分子影像重点实验室

	Performance investigation of SP3 and diffusion approximation for three-dimensional whole-body optical imaging of small animals
	Yang, Defu 1; Chen, Xueli 1; Cao, Xu 1; Wang, Jing 2; Liang, Jimin 1; Tian, Jie1,3
刊名	MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
	2015-09-01
卷号	53 期号:9 页码:805-814
关键词	Tissue classification criterion Performance investigation Third-order simplified harmonic spherical approximation Diffusion approximation Three-dimensional optical imaging
英文摘要	The third-order simplified harmonic spherical approximation (SP3) and diffusion approximation (DA) equations have been widely used in the three-dimensional (3D) whole-body optical imaging of small animals. With different types of tissues, which were classified by the ratio of A mu (s)'/A mu (E), the two equations have their own application scopes. However, the classification criterion was blurring and unreasonable, and the scope has not been systematically investigated until now. In this study, a new criterion for classifying tissues was established based on the absolute value of absorption and reduced scattering coefficients. Using the newly defined classification criterion, the performance and applicability of the SP3 and DA equations were evaluated with a series of investigation experiments. Extensive investigation results showed that the SP3 equation exhibited a better performance and wider applicability than the DA one in most of the observed cases, especially in tissues of low-scattering-low-absorption and low-scattering-high-absorption range. For the case of tissues with the high-scattering-low-absorption properties, a similar performance was observed for both the SP3 and the DA equations, in which case the DA was the preferred option for 3D whole-body optical imaging. Results of this study would provide significant reference for the study of hybrid light transport models.
WOS标题词	Science & Technology ; Technology ; Life Sciences & Biomedicine
类目[WOS]	Computer Science, Interdisciplinary Applications ; Engineering, Biomedical ; Mathematical & Computational Biology ; Medical Informatics
研究领域[WOS]	Computer Science ; Engineering ; Mathematical & Computational Biology ; Medical Informatics
关键词[WOS]	SIMPLIFIED SPHERICAL-HARMONICS ; LOW-SCATTERING ; BIOLUMINESCENCE TOMOGRAPHY ; PHOTON MIGRATION ; LIGHT TRANSPORT ; TURBID MEDIA ; REGIONS ; TISSUE ; RECONSTRUCTION ; PROPAGATION
收录类别	SCI
语种	英语
WOS记录号	WOS:000361491900004
公开日期	2015-12-24
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/9015]
专题	自动化研究所_中国科学院分子影像重点实验室
作者单位	1.Xidian Univ, Sch Life Sci & Technol, Engn Res Ctr Mol & Neuro Imaging, Minist Educ, Xian 710071, Shaanxi, Peoples R China 2.Fourth Mil Med Univ, Xijing Hosp, Dept Nucl Med, Xian 710032, Shaanxi, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Yang, Defu,Chen, Xueli,Cao, Xu,et al. Performance investigation of SP3 and diffusion approximation for three-dimensional whole-body optical imaging of small animals[J]. MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING,2015,53(9):805-814.
APA	Yang, Defu,Chen, Xueli,Cao, Xu,Wang, Jing,Liang, Jimin,&Tian, Jie.(2015).Performance investigation of SP3 and diffusion approximation for three-dimensional whole-body optical imaging of small animals.MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING,53(9),805-814.
MLA	Yang, Defu,et al."Performance investigation of SP3 and diffusion approximation for three-dimensional whole-body optical imaging of small animals".MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING 53.9(2015):805-814.