Multimodal Magnetic Resonance Imaging for Brain Disorders: Advances and Perspectives

	Multimodal Magnetic Resonance Imaging for Brain Disorders: Advances and Perspectives
	Jiang, Tianzi; Liu, Yong; Shi, Feng; Shu, Ni; Liu, Bing; Jiang, Jiefeng; Zhou, Yuan
刊名	BRAIN IMAGING AND BEHAVIOR
	2008-12-01
卷号	2 期号:4 页码:249-257
关键词	Magnetic resonance imaging Diffusion tensor imaging fMRI Imaging genetics Brain disorders
英文摘要	Modern brain imaging technologies play essential roles in our understanding of brain information processing and the mechanisms of brain disorders. Magnetic Resonance Imaging (MRI) and Diffusion Tensor Imaging (DTI) can image the anatomy and structure of the brain. In addition, functional MRI (fMRI) can identify active regions, patterns of functional connectivities and functional networks during either tasks that are specifically related to various aspects of brain function or during the resting state. The merging of such structural and functional information obtained from brain imaging may be able to enhance our understanding of how the brain works and how its diseases can occur. In this paper, we will review advances in both methodologies and clinical applications of multimodal MRI technologies, including MRI, DTI, and fMRI. We will also give our perspectives for the future in these fields. The ultimate goal of our study is to find early biomarkers based on multimodal neuroimages and genome datasets for brain disorders. More importantly, future studies should focus on detecting exactly where and how these brain disorders affect the human brain. It would also be also very interesting to identify the genetic basis of the anatomical and functional abnormalities in the brains of people who have neurological and psychiatric disorders. We believe that we can use brain images to obtain effective biomarkers for various brain disorders with the aid of developing computational methods and models.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Neuroimaging
研究领域[WOS]	Neurosciences & Neurology
关键词[WOS]	RESTING-STATE FMRI ; ALTERED FUNCTIONAL CONNECTIVITY ; FACTOR VAL66MET POLYMORPHISM ; WHITE-MATTER TRACTOGRAPHY ; PRIMARY VISUAL-CORTEX ; ALZHEIMERS-DISEASE ; SMALL-WORLD ; CEREBRAL-CORTEX ; DEFAULT-MODE ; ANATOMICAL CONNECTIVITY
收录类别	SCI
语种	英语
WOS记录号	WOS:000271090400004
公开日期	2015-12-24
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/9625]
专题	自动化研究所_09年以前成果
作者单位	Chinese Acad Sci, LIAMA Ctr Computat Med, Natl Lab Pattern Recognit, Inst Automat, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Jiang, Tianzi,Liu, Yong,Shi, Feng,et al. Multimodal Magnetic Resonance Imaging for Brain Disorders: Advances and Perspectives[J]. BRAIN IMAGING AND BEHAVIOR,2008,2(4):249-257.
APA	Jiang, Tianzi.,Liu, Yong.,Shi, Feng.,Shu, Ni.,Liu, Bing.,...&Zhou, Yuan.(2008).Multimodal Magnetic Resonance Imaging for Brain Disorders: Advances and Perspectives.BRAIN IMAGING AND BEHAVIOR,2(4),249-257.
MLA	Jiang, Tianzi,et al."Multimodal Magnetic Resonance Imaging for Brain Disorders: Advances and Perspectives".BRAIN IMAGING AND BEHAVIOR 2.4(2008):249-257.