A simplified edge illumination set-up for quantitative phase contrast mammography with synchrotron radiation at clinical doses

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	A simplified edge illumination set-up for quantitative phase contrast mammography with synchrotron radiation at clinical doses
	Longo, M; Rigon, L; Lopez, FCM; Chen, RC; Dreossi, D; Zanconati, F; Longo, R
刊名	PHYSICS IN MEDICINE AND BIOLOGY
	2015
卷号	60 期号:3 页码:N21—N34
关键词	IMAGING TECHNIQUE RAY TOMOGRAPHY
英文摘要	This work presents the first study of x-ray phase contrast imaging based on a simple implementation of the edge illumination method (EIXPCi) in the field of mammography with synchrotron radiation. A simplified EIXPCi set-up was utilized to study a possible application in mammography at clinical doses. Moreover, through a novel algorithm capable of separating and quantifying absorption and phase perturbations of images acquired in EIXPCi modality, it is possible to extract quantitative information on breast images, allowing an accurate tissue identification. The study was carried out at the SYRMEP beamline of Elettra synchrotron radiation facility (Trieste, Italy), where a mastectomy specimen was investigated with the EIXPCi technique. The sample was exposed at three different energies suitable for mammography with synchrotron radiation in order to test the validity of the novel algorithm in extracting values of linear attenuation coefficients integrated over the sample thickness. It is demonstrated that the quantitative data are in good agreement with the theoretical values of linear attenuation coefficients calculated on the hypothesis of the breast with a given composition. The results are promising and encourage the current efforts to apply the method in mammography with synchrotron radiation.
收录类别	SCI
语种	英语
公开日期	2015-12-24
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/24386]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
推荐引用方式 GB/T 7714	Longo, M,Rigon, L,Lopez, FCM,et al. A simplified edge illumination set-up for quantitative phase contrast mammography with synchrotron radiation at clinical doses[J]. PHYSICS IN MEDICINE AND BIOLOGY,2015,60(3):N21—N34.
APA	Longo, M.,Rigon, L.,Lopez, FCM.,Chen, RC.,Dreossi, D.,...&Longo, R.(2015).A simplified edge illumination set-up for quantitative phase contrast mammography with synchrotron radiation at clinical doses.PHYSICS IN MEDICINE AND BIOLOGY,60(3),N21—N34.
MLA	Longo, M,et al."A simplified edge illumination set-up for quantitative phase contrast mammography with synchrotron radiation at clinical doses".PHYSICS IN MEDICINE AND BIOLOGY 60.3(2015):N21—N34.