Potential ecotoxic effects of polychlorinated biphenyls on Xenopus laevis

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Potential ecotoxic effects of polychlorinated biphenyls on Xenopus laevis
	Qin, ZF; Zhou, JM; Cong, L; Xu, XB
刊名	ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
	2005
卷号	24 期号:10 页码:2573-2578
关键词	polychlorinated biphenyls Xenopus laevis malformation gonad amphibian population
英文摘要	We examined potential ecotoxic effects of polychlorinated biphenyl (PCB)(3), PCB5, Aroclor 1254, and Aroclor 1242 on Xenopus laevis. Tadpoles were exposed to PCBs from stage 46/47 (system of Nieuwkoop and Faber) to the completion of metamorphosis. We demonstrated, to out, knowledge for the first time, forelimb malformations caused by PCBs (malformation rate, > 70%). The malformed forelimbs were fixed in the adduction-backward rotation position and could not move. Therefore, malformed male frogs were destined to have no offspring, because they could not grasp the females with their forelimbs to mate. Alcian blue-alizarin red double-staining indicated that the forelimb malformation resulted from the shoulder abnormality. Compared with the normal shoulder joint, the proximal humerus with the humerus inter-rotated 90 degrees in the abnormal shoulder joint. Moreover, testes from more than a third of male frogs with exposed to PCBs exhibited feminization to different degrees at gross morphology and histology, with fewer or abnormal spermatogonia and oocytes. Gonadal abnormalities would lead directly to reproductive dysfunction and Population decline. These results suggest that PCBs have potentially ecotoxic effects on amphibian populations. We infer that PCBs could play roles in amphibian malformations and population declines, at least at sites that are polluted heavily with PCBs.
学科主题	Environmental Sciences & Ecology; Toxicology
研究领域[WOS]	Environmental Sciences & Ecology ; Toxicology
WOS记录号	WOS:000232264400020
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/23208]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Qin, ZF,Zhou, JM,Cong, L,et al. Potential ecotoxic effects of polychlorinated biphenyls on Xenopus laevis[J]. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY,2005,24(10):2573-2578.
APA	Qin, ZF,Zhou, JM,Cong, L,&Xu, XB.(2005).Potential ecotoxic effects of polychlorinated biphenyls on Xenopus laevis.ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY,24(10),2573-2578.
MLA	Qin, ZF,et al."Potential ecotoxic effects of polychlorinated biphenyls on Xenopus laevis".ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 24.10(2005):2573-2578.